Steroids, Sterols and The Nervous System
Steroids are based on the cyclopentanoperhydrophenanthrene structure and belong to isoprenoid family, and abnormalities in their synthesis is related to numerous diseases. Mostly steroid hormones are ligands to nuclear receptor and mutations in receptor and may change its ligand specificity resulting in allowing them for binding to other steroids, and thus physiological changes. This track will concentrate on analysis of steroids.
- Analysis by mass spectroscopy
- Linking proteomics with lipidomics
- Metabolite profiling in brain- neurosteroids & neurosterols
- Steroids, neurosteroids, oxysterols and neurosterols